Although nootropics can be both organic and synthetic, the synthetic drugs belonging to the racetam type are currently considered the best nootropics (2017). The effects and benefits of racetams have been studied since the mid-20th century, and racetam research has consistently shown that these unique and powerful drugs benefit the brain in a number of ways.
Despite all of the research involving racetams, scientists cannot definitively say how racetams work. After all, the brain is the body’s most complex organ. Racetams are believed to work by modulating neurotransmitters like acetylcholine and glutamate in the brain. Many racetams also work by increasing the firing rate of cholinergic receptors, which are linked to memory formation. In addition, certain types of racetams increase the amount of communication that takes place between the left and right sides of the brain across the corpus collosum. The brain undergoes other processes while taking racetams, although the full extent of these processes it not yet understood.
It’s important to note that none of these processes can damage the brain. Racetams have been used for many years, and although the full power of racetams is not yet understood, side effects are minimal. After taking an excessive dosage of racetams, some users reportedly experienced headaches and nausea, although these doses were far in excess of the recommended daily amount that an average user should take.
After taking racetams, users report feeling increased mental clarity as well as focus and calmness. When tested, racetam users have an easier time recalling facts and techniques. From spatial thinking to problem analysis, racetams are a safe and effective way to use the brain to its full potential.
If you’re interested in learning more about racetams, then keep reading.
How Do Nootropics Improve The Brain?
Racetams improve the brain in a variety of ways. Some racetams will improve the brain in one specific way, while others offer comprehensive cognitive enhancement. Here are a few of the most popular ways in which racetams improve the brain:
- Increased intellect and higher intelligence levels (measured by IQ tests)
- Increased ability to focus; better attention span
- Enhanced spatial memory
- Faster neurological connections in the brain
- Increased memory retention
- Better cardiovascular health in the brain and throughout the rest of the body
- Increased oxygen and nutrient levels in the brain
- General cognitive enhancements in terms of the speed and performance of the brain
- Delayed onset of degenerative brain diseases like dementia, Alzheimer’s, and Parkinson’s
So how do racetams actually work? Well, most racetams work by altering receptors and neurotransmitters in the brain. In general, racetams are thought to activate glutamate receptors. Since many glutamate receptors are colocalized with cholinergic receptors, this increases the firing of the cholinergic receptors, which has been shown to enhance memory retention and increase cognitive ability in a number of ways.
In addition, studies have consistently demonstrated that racetams are more effective when paired with choline. Choline is simply a water-soluble nutrient that is important for a number of different bodily functions. It’s used to create new components in body cell membranes, and many foods like eggs and fatty meats contain choline.
Those interested in taking racetams on a regular basis should make sure to integrate enough choline into their diet. The average amount of choline required by a healthy adult is between 425 to 550mg per day. Choline can be found in all of the following foods:
- Raw beef liver
- Hardboiled eggs (113mg of Choline per egg)
- Cod fish
- Milk (173mg of Choline in one quart of milk)
- Brown rice
Which are the best Nootropics?
Racetams have been researched for nearly half a century. As such, there are plenty of studies that have reinforced the power of racetams. Here are a few of the most conclusive studies involving racetams:
–Piracetam study and cognitive ability: Piracetam is one of the most popular types of racetams available today. In one study, Piracetam and Oxiracetam were studied to determine the effects on learning and cognitive processes. The study, performed by G. Spignoli et al. in 1986, concluded that both Piracetam and Oxiracetam increased the activity of the cortical cholinergic network, which is a critical factor in many cognitive processes. Rats who took these racetams learned how to avoid electric shocks much faster than rats that were simply injected with a saline solution.
-Piracetam study on memory retention and aging: A similar study performed by Raymond T. Bartus et. al in 1981 showed that Piracetam could be used to improve memory in older rats. The administration of Piracetam significantly increased performance on a passive avoidance task. And, when exposed to Piracetam over the length of a week, rats showed significantly higher results than if they were administered to just a single dose of Piracetam. Memory was shown to increase when rats avoided entering the dark half of a two-chambered box to avoid an electric shock.
-Racetams aid the fight against Alzheimer’s and dementia: Racetams improve the functioning of the brain in a variety of ways, but one benefit that many people have not considered is that racetams can delay the onset of Alzheimer’s and dementia. In this study, a racetam compound was shown to have positive benefits on the hippocampus, improving its synaptic function and plasticity and ultimately delaying the onset of degenerative brain conditions.
-Racetams shown to prevent seizures and epilepsy: Although different from Alzheimer’s and dementia, seizures and epilepsy are equally as dangerous brain conditions. A specific type of racetam called Levetiracetam (LEV) has been shown to reduce instances of epilepsy and seizures, making it a valuable tool for the medical community. This effect was demonstrated in both this study from 2005 and this study from 2011.
Piracetam tends to be the most popular and best nootropic available today, although it’s bigger brother – Pramiracetam – has been gaining grounds as an even more poweful alternative.